Abstract: Based on the latest research results of geological structures in “Regional Geology in Jiangxi Province”, and earthquake records provided by Seismic Administration of Jiangxi Province, this study analyzes neotectonic framework, seismic activity characteristics and dynamic mechanism in Jiangxi Province. The result shows that the distribution of epicenters in Jiangxi is related to the neotectonic framework, with seismic activities occurring mainly in the NNE-trending Mufushan-Luoxiaoshan seismic active belt and the southern part of the Huaiyushan-Wuyishan-Jiulianshan seismic active belt. Main destructive seismic faults and tectonic environment of seismogenic zones in Jiangxi have been further clarified, which can provide important basis for optimizing seismic zoning, seismic monitoring and earthquake prevention.