Abstract: By studying on the ore-controlling structural factors of the Tianjingshan gold deposit and Xiaohe lead-zinc deposit inXiuning, Anhui Province, it is considered that the late Yanshanian granite and NE-trending faults are the most important ore-controlling factors of the gold polymetallic mineralization. Detailed structural analysis of Nanyuankou in Shexianand Taoxi in Xiuning indicates that since the Mesozoic Era, the two areas experienced four deformation stages. Among them, early northwestern thrusting and NNE-trending strike-slip fault were Pre-mineralization structures, and the NE-trending high-angle normal fault that controlled the intrusion and mineralization oflate Yanshanian granite was mineralization structure. And the following right-lateral strike-slip faults were post-mineralization structure.