Abstract: The database of 1:50 000 regional geological map is the most fundamental and important database in national basic geological databases, and its quality is directly affected by the process of database construction and the methods of controlling quality. On the basis of 778 map-sheets of 1:50 000 regional geological databases in East China, the paper discussed the technical process, work means and quality control of 1:50 000 regional geological databases and their application and effect. Precise database modelling, unified methods of constructing database and overall quality-controlling process are the necessary preconditions for ensuring the quality of the databases. The management system of the geological map databases can realize the systemic management and sharing of the 1:50 000 regional geological map databases of East China.