Abstract: In this paper, we used the Analytic Hierarchy Process(AHP)and fuzzy mathematics to carry out the comprehensive assessment of mine environment in the southern part of the Sanjiang metallogenic belt. The results show that the assessment factors of mine environment, defined by AHP and sorted according to weight values, are successively vegetation importance, land use, topography, mining geological hazards, soil erosion and mining development area. The comprehensive assessment results using fuzzy mathematics suggest that the regional mine environment can be classified into the first grade “good”. The assessment factors were superimposed in the GIS platform to form diagrams based on their weight values, obtaining mine environment assessment data for mineral resources development zone in the south of the Sanjiang metallgoenic belt. Analytic Hierarchy Process(AHP)and fuzzy mathematics were employed to comprehensively assess regional mining environment, which considers not only the environmental impact factors of the mine but also the advantages of the two mathematical methods in the ways of dynamic and static, quantitative and non quantitative indicators. Therefore, this fuzziness of factors and process has not only reduced objectiveness of experts’ assessment, but made the assessment results more practical, providing references for mining supervision and environmental treatment of regional mines.