Abstract: As an effective indicator for low-middle temperature minerals related to mineralization, infrared spectrum has been extensively employed in-site mineral mapping. This high technology is characterized by high sampling density, large data volume, high efficiency and low cost. With an emphasis on introduction to the latest development and status of infrared spectroscopy instrument and application of Domestic CMS350A digital core scanner, this study presents application of the technique and its results. On the basis of mineralization and alteration features outlined by mass data, the study precisely indentified altered minerals which are significant to prospecting, obtained ion exchange data of minerals and deduced the properties of hydrothemal fluid, providing guidance for potential evaluation of regional prospecting and further deployment for mineral exploration. Thus, the study direction of infrared spectrum mineral mapping technology should focus on the outreach of working band toward thermal infrared, miniaturization of equipment, improvement of spectral resolution and expansion of applicable fields, etc.