Abstract: High-density resistivity method has been applied to explore groundwater and soil pollution of NH chemical plant in the south of Jiangsu in this paper. The results indicate that there are several anomaly areas with high resistance more than 100 Ω·m in the aquifer underground of 17～45 m. The anomaly areas virtually are pollution plumes of dense non-aqueous phase liquids with high concentrations, which are verified by drilling and chemical analysis. According to the characteristics of anomaly areas, further exploration has been carried out in the site to identify spatial distribution, sources and migration of underground pollutants. The study shows that the application of high-density resistivity method to explore organic pollution of groundwater and soil in chemical plants is effective, economic and convenient. It is recommended to popularize the method in the exploration of organic pollution plume.