Abstract: Based on the latest gravity and magnetic data, the surface geological and drilling information in the Xujiazui region, a detailed geology-geophysical model is established by using 2.5D gravity and magnetic joint inversion method in this paper. The model is used to clarify the relationship between the deep diorite, the sulfate evaporate salt layers and porphyry iron deposit, so as to guide the ore-prospecting in the Xiahanshan region, Xujiazui in the southwest margin of the Luzong basin. The result shows that the monzodiorite was emplaced at depth of 1200m, and the sulfate evaporate salt layers interbedded with magnetite in the contact zone between the intrusion and the Triassic Yueshan Formation, which is similar with the "Longqiao-type" mineralization. This study suggests that the porphyry iron mineralization in the Luzong basin is closely related to diorite and sulfate evaporate salt layers. Based on the research, two prospecting targets are delineated in the Xiahanshan uplift zone in the Xujiazui region, providing direction for the further ore-prospecting. Consequently, the geological-geophysical modeling technique has been proved to be an effective method of guiding mineral exploration.