Abstract: Based on the systematic sampling and analysis of the four drill cores in the exploration line 18 of Huangtun copper-gold deposit in Lujiang, Anhui Province, this paper studies the geological characteristics and primary halo zoning characteristics of the exploration line18, preliminary summarizes the geochemical anomaly pattern of the deposit, and explores the possible genesis of Huangtun copper-gold deposit. Au, Ag, Cu, As, Sb, Bi and W are the characteristic element assemblage of Huangtun copper-gold deposit, and the vertical zoning sequence of the primary halo of this deposit is (Sb, As)-(Ag, Au, Cu)-(Bi, W). The geological characteristics and primary halo morphology of the exploration line 18 show that there may be a hidden fault between the borehole ZK18-1 and ZK18-2, resulting in dislocation of copper-gold ore body and stratum. Element association anomaly of front halo in hydrothermal deposit is developed at the bottom of borehole TK02, indicating that there may be concealed ore bodies in the deep. The comprehensive study shows that the ore-forming materials of Huangtun copper-gold deposit may be mainly derived from volcanic hydrothermal and diorite porphyrite, and this deposit belongs to volcanic-subvolcanic hydrothermal type.