Abstract: Based on the 1:50 000 hydrogeological and environmental geological survey, the characteristics of karst development and the law of groundwater enrichment in Shazhouba area of Ruijin City were studied by means of drilling. The results show that the karst development is controlled by geological structure, topography and other factors, leading to uneven karst development in this area. The small solution hole is only 0.1 cm, while the large one is 231.92 m high. The heterogeneity of karst development results in the obvious difference of water content of karst aquifer, and the occurrence and enrichment of groundwater are closely related to lithology, structure, karst development degree and recharge condition. According to the comprehensive analysis, the karsts mainly develop in the shallow part along the structure, the layer of the soluble rock, and the pure karst. Karst groundwater is mainly concentrated in fault zones and their composite parts, groundwater discharge areas and main runoff zones, shallow parts, folds and turning points of fault structures. To find out the characteristics of karst development and the law of groundwater enrichment in Shazhouba area may provide scientific basis for the site selection of important projects construction and the prevention and control of geo-hazards such as karst collapse.